Journal: Archives Animal Breeding

Article Title: Expression profiles and polymorphic identification of the ACSL1 gene and their association with body size traits in Dezhou donkeys

doi: 10.5194/aab-63-377-2020

Figure Lengend Snippet: Primer information of Dezhou donkey ACSL1 and GAPDH genes for qPCR and ACSL1 polymorphic sites.

Article Snippet: However, there are few studies on the ACSL1 gene polymorphism of Dezhou donkeys.

Techniques:

Journal: Archives Animal Breeding

Article Title: Expression profiles and polymorphic identification of the ACSL1 gene and their association with body size traits in Dezhou donkeys

doi: 10.5194/aab-63-377-2020

Figure Lengend Snippet: Detection of genotype frequencies, allele frequencies and population genetic parameters of ACSL1 gene mutation loci in Dezhou donkeys of different genders.

Article Snippet: However, there are few studies on the ACSL1 gene polymorphism of Dezhou donkeys.

Techniques: Mutagenesis

Journal: Archives Animal Breeding

Article Title: Expression profiles and polymorphic identification of the ACSL1 gene and their association with body size traits in Dezhou donkeys

doi: 10.5194/aab-63-377-2020

Figure Lengend Snippet: Haplotypes of the four sites within the ACSL1 gene in Dezhou donkeys of different genders.

Article Snippet: However, there are few studies on the ACSL1 gene polymorphism of Dezhou donkeys.

Techniques:

Journal: Archives Animal Breeding

Article Title: Expression profiles and polymorphic identification of the ACSL1 gene and their association with body size traits in Dezhou donkeys

doi: 10.5194/aab-63-377-2020

Figure Lengend Snippet: Association between ACSL1 gene mutation loci and growth traits in Dezhou donkeys of different genders.

Article Snippet: However, there are few studies on the ACSL1 gene polymorphism of Dezhou donkeys.

Techniques: Mutagenesis

Journal: Archives Animal Breeding

Article Title: Expression profiles and polymorphic identification of the ACSL1 gene and their association with body size traits in Dezhou donkeys

doi: 10.5194/aab-63-377-2020

Figure Lengend Snippet: Association analysis between combined haplotypes of the ACSL1 gene and growth traits in the Dezhou donkey.

Article Snippet: However, there are few studies on the ACSL1 gene polymorphism of Dezhou donkeys.

Techniques:

Journal: Genes

Article Title: Association of HOXC8 Genetic Polymorphisms with Multi-Vertebral Number and Carcass Weight in Dezhou Donkey

doi: 10.3390/genes13112175

Figure Lengend Snippet: Sequencing profiles around three mutation loci in the HOXC8 of Dezhou donkeys. The upper panels represent the reference genome, and the lower panels represent the variant.

Article Snippet: Then, a general linear model was used to perform an association study of HOXC8 gene polymorphism loci, multiple vertebral numbers, and carcass weight for screening candidate markers that can be used for molecular breeding of Dezhou donkeys.

Techniques: Sequencing, Mutagenesis, Variant Assay

Journal: Genes

Article Title: Association of HOXC8 Genetic Polymorphisms with Multi-Vertebral Number and Carcass Weight in Dezhou Donkey

doi: 10.3390/genes13112175

Figure Lengend Snippet: The information of 12 mutation loci in the HOXC8 gene of Dezhou donkeys.

Article Snippet: Then, a general linear model was used to perform an association study of HOXC8 gene polymorphism loci, multiple vertebral numbers, and carcass weight for screening candidate markers that can be used for molecular breeding of Dezhou donkeys.

Techniques: Mutagenesis, Residue

Journal: Genes

Article Title: Association of HOXC8 Genetic Polymorphisms with Multi-Vertebral Number and Carcass Weight in Dezhou Donkey

doi: 10.3390/genes13112175

Figure Lengend Snippet: Population genetic analysis of 4 SNPs of the HOXC8 mutation in Dezhou donkeys.

Article Snippet: Then, a general linear model was used to perform an association study of HOXC8 gene polymorphism loci, multiple vertebral numbers, and carcass weight for screening candidate markers that can be used for molecular breeding of Dezhou donkeys.

Techniques: Mutagenesis

Journal: Genes

Article Title: Association of HOXC8 Genetic Polymorphisms with Multi-Vertebral Number and Carcass Weight in Dezhou Donkey

doi: 10.3390/genes13112175

Figure Lengend Snippet: The phylogenetic tree of the HOXC8 gene in different species. The number on the internal node represents support value and is used to represent the reliability of this branch structure.

Article Snippet: Then, a general linear model was used to perform an association study of HOXC8 gene polymorphism loci, multiple vertebral numbers, and carcass weight for screening candidate markers that can be used for molecular breeding of Dezhou donkeys.

Techniques:

Journal: Metabolic brain disease

Article Title: Krüpple-like factors in the central nervous system: novel mediators in Stroke

doi: 10.1007/s11011-013-9468-1

Figure Lengend Snippet: Biological function of KLFs in the nervous system

Article Snippet: It is worth noting that KLF11 is a member of the KLF family with high expression in vascular endothelium ( Fan et al., 2012 ), and emerging data from population genetics studies suggest that KLF11 gene single nucleotide polymorphisms (SNPs) are significantly associated with type 2 diabetes ( Neve et al., 2005 ; Fernandez-Zapico et al., 2009 ).

Techniques: Migration, Activation Assay

Journal: Metabolic brain disease

Article Title: Krüpple-like factors in the central nervous system: novel mediators in Stroke

doi: 10.1007/s11011-013-9468-1

Figure Lengend Snippet: Schematic representation of stroke-associated KLFs and signaling cascades. KLF4 is induced in reactive astrocytes in rat hippocampus after global cerebral ischemia, and may transcriptionally regulate astroglial reaction and cerebral inflammation following ischemic injury (Park et al., 2013). KLF2 level is decreased in blood outgrowth endothelial cells (BOECs) derived from stroke children with sickle cell anemia (SCA) than in non-SCA BOECs, thus changes the ratio between proinflammatory NF-κB/p65 to anti-inflammatory factor KLF2 and leads to a proinflammatory phenotype within the cerebral vasculature (Enenstein et al., 2010). In mouse brain vasculature, ischemic stimuli induce KLF2 (Shi et al., 2013) or KLF11 dysfunction (Yin et al., 2013), featuring attenuated KLF2 transactivation of tight junction protein occludin or reduced KLF11-mediated PPARγ vascular function, thereby resulting in a series of cerebral vascular pathologies, such as BBB damage/dysfunction, disturbed cerebral vascular protection, and final neuronal cell death.

Article Snippet: It is worth noting that KLF11 is a member of the KLF family with high expression in vascular endothelium ( Fan et al., 2012 ), and emerging data from population genetics studies suggest that KLF11 gene single nucleotide polymorphisms (SNPs) are significantly associated with type 2 diabetes ( Neve et al., 2005 ; Fernandez-Zapico et al., 2009 ).

Techniques: Derivative Assay

Journal: Metabolic brain disease

Article Title: Krüpple-like factors in the central nervous system: novel mediators in Stroke

doi: 10.1007/s11011-013-9468-1

Figure Lengend Snippet: KLFs involved in neurological disorders

Article Snippet: It is worth noting that KLF11 is a member of the KLF family with high expression in vascular endothelium ( Fan et al., 2012 ), and emerging data from population genetics studies suggest that KLF11 gene single nucleotide polymorphisms (SNPs) are significantly associated with type 2 diabetes ( Neve et al., 2005 ; Fernandez-Zapico et al., 2009 ).

Techniques: Expressing, Over Expression, Activation Assay, Transmission Assay